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1.
Complement Ther Med ; 64: 102798, 2022 Mar.
Artículo en Inglés | MEDLINE | ID: covidwho-1654290

RESUMEN

BACKGROUND: Passive heat therapies have been reported to have similar effects on the cardiovascular system as exercise. Studies supporting these findings in healthy populations have predominantly been done with men using warm water immersions or traditional saunas, rather than newer infrared-based saunas. OBJECTIVE: To explore short-term thermal and cardiovascular responses in women using an infrared sauna as compared to moderate-intensity exercise. STUDY DESIGN: Randomized controlled crossover trial with balanced allocations. SETTING: Brisbane, Australia (August 2019 - March 2020) PARTICIPANTS: Ten healthy women (36 ±â€¯9 years) INTERVENTIONS: 45 min of resting, infrared sauna or indoor bicycling PRIMARY OUTCOME MEASURES: tympanic/skin temperatures; respiratory rate; blood pressure; arterial stiffness; heart rate variability RESULTS: Tympanic temperatures were elevated during infrared sauna as compared to both control (mean diff = +1.05 oC ±â€¯SEM 0.12 oC, 95% C.I.: 0.73 - 1.36, p < 0.0005) and exercise (mean diff = +0.79 oC ±â€¯SEM 0.12 oC, 95% C.I.: 0.49 - 1.08, p < 0.0005). Respiratory rates were higher during exercise as compared to both control (mean diff = +7.66 ±â€¯SEM 1.37, 95% C.I.: 4.09 - 11.23, p < 0.0005) and infrared sauna (mean diff = +6.66 ±â€¯SEM 1.33, 95% C.I.: 3.20 - 10.11, p < 0.0005). No significant differences in non-invasive measures of blood pressure, arterial stiffness or heart rate variability were detected between any of the interventions. CONCLUSIONS: These findings suggest the physiological effects of infrared sauna bathing are underpinned by thermoregulatory-induced responses, more so than exercise-mimetic cardiorespiratory or cardiovascular activations.


Asunto(s)
Baño de Vapor , Presión Sanguínea , Estudios Cruzados , Ejercicio Físico , Femenino , Frecuencia Cardíaca , Humanos , Masculino
2.
Innovation in aging ; 5(Suppl 1):952-952, 2021.
Artículo en Inglés | EuropePMC | ID: covidwho-1602418

RESUMEN

Despite the start of COVID-19 pandemic recovery in the U.S., food insecurity remains at elevated levels with 10% of American adults reporting food insecurity nearly three times higher than pre-pandemic (Census Bureau’s Household Pulse Survey, June 2021). To gain insight into the long-term impacts of the pandemic on older adults, we examined food insecurity patterns during the last economic recession and the role that the Supplemental Nutrition Assistance Program (SNAP) played in mitigating food insecurity and skipped meals. We analyzed data on adults age 60+ from the Health and Retirement Study, looking at the Great Recession (2008) as a predictor of what to expect in the next decade of pandemic recovery. A key finding was that food insecurity more than doubled among older adults during the Great Recession and remained elevated even 10 years later. Regression analyses showed that SNAP use among older adults weakened the relationship between poverty and food insecurity, but didn’t eliminate it—17% of older adults still reported food insecurity two years after enrolling in SNAP. The data indicates that a growing share of older SNAP users’ benefits have not kept up with rising food costs. In fact, 85% of beneficiaries had monthly benefit amounts below the USDA ‘Thrifty Plan” budget. Congress recently passed the American Rescue Plan which increases SNAP benefits temporarily, yet these enhancements are about to run out. This study underscores the need for permanent SNAP enhancements to help prevent long-lasting hunger facing millions of older Americans.

3.
Innovation in Aging ; 5(Supplement_1):504-504, 2021.
Artículo en Inglés | PMC | ID: covidwho-1584519

RESUMEN

Medicaid financing of nursing home (NH) care provides the strongest safety net for low income older adults, persons who have high-intensity long-term care (LTC) needs, and consumers with exorbitant LTC costs. Yet, NHs currently face serious threats to their financial viability, particularly in the context of the COVID-19 pandemic, where the costs of caring for residents in a safe way have increased significantly, even as the ability to recoup these costs from the Medicaid program has been constrained. The purpose of this study is to assess key demand and supply factors affecting the performance of the NH industry in Pennsylvania over time. It draws from several large, national data sources, including NH Compare, LTCFocus.org, the U.S. Bureaus of the Census and Labor Statistics, and Certification and Survey Provider Enhanced Reports, as well as state-level population projections and Departments of Health and Human Services data. An aggregate database was constructed with historical data points at the facility, regional, and state level. Annual total and regional trends were examined from 2010 to 2020. Findings suggest a growing gap between what NHs require to meet the needs of residents and the level of reimbursement paid by the largest funder: Medicaid. Considering demographic trends, this gap will only grow over time in the absence of policy change. The pandemic has further highlighted the existing challenges resulting from an underfunded service infrastructure and the need for additional investment if NHs are to provide high quality care to a growing cohort of older adults requiring support.

4.
J Clin Med ; 9(12)2020 Dec 21.
Artículo en Inglés | MEDLINE | ID: covidwho-1463718

RESUMEN

Patients receiving mechanical ventilation for coronavirus disease 2019 (COVID-19) related, moderate-to-severe acute respiratory distress syndrome (CARDS) have mortality rates between 76-98%. The objective of this retrospective cohort study was to identify differences in prone ventilation effects on oxygenation, pulmonary infiltrates (as observed on chest X-ray (CXR)), and systemic inflammation in CARDS patients by survivorship and to identify baseline characteristics associated with survival after prone ventilation. The study cohort included 23 patients with moderate-to-severe CARDS who received prone ventilation for ≥16 h/day and was segmented by living status: living (n = 6) and deceased (n = 17). Immediately after prone ventilation, PaO2/FiO2 improved by 108% (p < 0.03) for the living and 150% (p < 3 × 10-4) for the deceased. However, the 48 h change in lung infiltrate severity in gravity-dependent lung zones was significantly better for the living than for the deceased (p < 0.02). In CXRs of the lower lungs before prone ventilation, we observed 5 patients with confluent infiltrates bilaterally, 12 patients with ground-glass opacities (GGOs) bilaterally, and 6 patients with mixed infiltrate patterns; 80% of patients with confluent infiltrates were alive vs. 8% of patients with GGOs. In conclusion, our small study indicates that CXRs may offer clinical utility in selecting patients with moderate-to-severe CARDS who will benefit from prone ventilation. Additionally, our study suggests that lung infiltrate severity may be a better indicator of patient disposition after prone ventilation than PaO2/FiO2.

5.
JAMA Intern Med ; 181(12): 1612-1620, 2021 12 01.
Artículo en Inglés | MEDLINE | ID: covidwho-1453495

RESUMEN

Importance: Hospitalized patients with COVID-19 are at risk for venous and arterial thromboembolism and death. Optimal thromboprophylaxis dosing in high-risk patients is unknown. Objective: To evaluate the effects of therapeutic-dose low-molecular-weight heparin (LMWH) vs institutional standard prophylactic or intermediate-dose heparins for thromboprophylaxis in high-risk hospitalized patients with COVID-19. Design, Setting, and Participants: The HEP-COVID multicenter randomized clinical trial recruited hospitalized adult patients with COVID-19 with D-dimer levels more than 4 times the upper limit of normal or sepsis-induced coagulopathy score of 4 or greater from May 8, 2020, through May 14, 2021, at 12 academic centers in the US. Interventions: Patients were randomized to institutional standard prophylactic or intermediate-dose LMWH or unfractionated heparin vs therapeutic-dose enoxaparin, 1 mg/kg subcutaneous, twice daily if creatinine clearance was 30 mL/min/1.73 m2 or greater (0.5 mg/kg twice daily if creatinine clearance was 15-29 mL/min/1.73 m2) throughout hospitalization. Patients were stratified at the time of randomization based on intensive care unit (ICU) or non-ICU status. Main Outcomes and Measures: The primary efficacy outcome was venous thromboembolism (VTE), arterial thromboembolism (ATE), or death from any cause, and the principal safety outcome was major bleeding at 30 ± 2 days. Data were collected and adjudicated locally by blinded investigators via imaging, laboratory, and health record data. Results: Of 257 patients randomized, 253 were included in the analysis (mean [SD] age, 66.7 [14.0] years; men, 136 [53.8%]; women, 117 [46.2%]); 249 patients (98.4%) met inclusion criteria based on D-dimer elevation and 83 patients (32.8%) were stratified as ICU-level care. There were 124 patients (49%) in the standard-dose vs 129 patients (51%) in the therapeutic-dose group. The primary efficacy outcome was met in 52 of 124 patients (41.9%) (28.2% VTE, 3.2% ATE, 25.0% death) with standard-dose heparins vs 37 of 129 patients (28.7%) (11.7% VTE, 3.2% ATE, 19.4% death) with therapeutic-dose LMWH (relative risk [RR], 0.68; 95% CI, 0.49-0.96; P = .03), including a reduction in thromboembolism (29.0% vs 10.9%; RR, 0.37; 95% CI, 0.21-0.66; P < .001). The incidence of major bleeding was 1.6% with standard-dose vs 4.7% with therapeutic-dose heparins (RR, 2.88; 95% CI, 0.59-14.02; P = .17). The primary efficacy outcome was reduced in non-ICU patients (36.1% vs 16.7%; RR, 0.46; 95% CI, 0.27-0.81; P = .004) but not ICU patients (55.3% vs 51.1%; RR, 0.92; 95% CI, 0.62-1.39; P = .71). Conclusions and Relevance: In this randomized clinical trial, therapeutic-dose LMWH reduced major thromboembolism and death compared with institutional standard heparin thromboprophylaxis among inpatients with COVID-19 with very elevated D-dimer levels. The treatment effect was not seen in ICU patients. Trial Registration: ClinicalTrials.gov Identifier: NCT04401293.


Asunto(s)
Anticoagulantes/administración & dosificación , COVID-19/diagnóstico , Enoxaparina/administración & dosificación , Heparina de Bajo-Peso-Molecular/administración & dosificación , Heparina/administración & dosificación , Mortalidad Hospitalaria , Pacientes Internos , Tromboembolia Venosa/prevención & control , Adulto , Anciano , COVID-19/sangre , COVID-19/terapia , Femenino , Productos de Degradación de Fibrina-Fibrinógeno/análisis , Hospitalización , Humanos , Unidades de Cuidados Intensivos , Masculino , SARS-CoV-2 , Resultado del Tratamiento
6.
J Ambul Care Manage ; 44(4): 293-303, 2021.
Artículo en Inglés | MEDLINE | ID: covidwho-1447660

RESUMEN

COVID-19 necessitated significant care redesign, including new ambulatory workflows to handle surge volumes, protect patients and staff, and ensure timely reliable care. Opportunities also exist to harvest lessons from workflow innovations to benefit routine care. We describe a dedicated COVID-19 ambulatory unit for closing testing and follow-up loops characterized by standardized workflows and electronic communication, documentation, and order placement. More than 85% of follow-ups were completed within 24 hours, with no observed staff, nor patient infections associated with unit operations. Identified issues include role confusion, staffing and gatekeeping bottlenecks, and patient reluctance to visit in person or discuss concerns with phone screeners.


Asunto(s)
Instituciones de Atención Ambulatoria/organización & administración , COVID-19/terapia , Continuidad de la Atención al Paciente/organización & administración , Neumonía Viral/terapia , Unidades de Cuidados Respiratorios/organización & administración , Adulto , Anciano , Boston/epidemiología , COVID-19/epidemiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neumonía Viral/epidemiología , Neumonía Viral/virología , Derivación y Consulta/estadística & datos numéricos , SARS-CoV-2 , Análisis de Sistemas , Flujo de Trabajo
9.
Thromb Haemost ; 121(12): 1684-1695, 2021 12.
Artículo en Inglés | MEDLINE | ID: covidwho-1171416

RESUMEN

Coronavirus disease-2019 (COVID-19) has been associated with significant risk of venous thromboembolism (VTE), arterial thromboembolism (ATE), and mortality particularly among hospitalized patients with critical illness and elevated D-dimer (Dd) levels. Conflicting data have yet to elucidate optimal thromboprophylaxis dosing. HEP-COVID (NCT04401293) is a phase 3, multicenter, pragmatic, prospective, randomized, pseudo-blinded, active control trial to evaluate efficacy and safety of therapeutic-dose low-molecular-weight heparin (LMWH) versus prophylactic-/intermediate-dose LMWH or unfractionated heparin (UFH) for prevention of a primary efficacy composite outcome of VTE, ATE, and all-cause mortality 30 ± 2 days post-enrollment. Eligible patients have COVID-19 diagnosis by nasal swab or serologic testing, requirement for supplemental oxygen per investigator judgment, and Dd >4 × upper limit of normal (ULN) or sepsis-induced coagulopathy score ≥4. Subjects are randomized to enoxaparin 1 mg/kg subcutaneous (SQ)/two times a day (BID) (creatinine clearance [CrCl] ≥ 30 mL/min) or 0.5 mg/kg (CrCl 15-30 mL/min) versus local institutional prophylactic regimens including (1) UFH up to 22,500 IU (international unit) daily (divided BID or three times a day), (2) enoxaparin 30 and 40 mg SQ QD (once daily) or BID, or (3) dalteparin 2,500 IU or 5,000 IU QD. The principal safety outcome is major bleeding. Events are adjudicated locally. Based on expected 40% relative risk reduction with treatment-dose compared with prophylactic-dose prophylaxis, 308 subjects will be enrolled (assuming 20% drop-out) to achieve 80% power. Distinguishing design features include an enriched population for the composite endpoint anchored on Dd >4 × ULN, stratification by intensive care unit (ICU) versus non-ICU, and the ability to capture asymptomatic proximal deep venous thrombosis via screening ultrasonography prior to discharge.


Asunto(s)
Anticoagulantes/administración & dosificación , Tratamiento Farmacológico de COVID-19 , Enoxaparina/administración & dosificación , Tromboembolia/tratamiento farmacológico , Anticoagulantes/efectos adversos , COVID-19/complicaciones , COVID-19/diagnóstico , Ensayos Clínicos Fase III como Asunto , Enoxaparina/efectos adversos , Humanos , Ensayos Clínicos Pragmáticos como Asunto , Estudios Prospectivos , Medición de Riesgo , Factores de Riesgo , Tromboembolia/diagnóstico , Tromboembolia/etiología , Factores de Tiempo , Resultado del Tratamiento , Estados Unidos , Tromboembolia Venosa/diagnóstico , Tromboembolia Venosa/etiología , Tromboembolia Venosa/prevención & control
10.
Res Aging ; 43(3-4): 123-126, 2021.
Artículo en Inglés | MEDLINE | ID: covidwho-1061209

RESUMEN

This special issue covers several important topics related to long-term care (LTC) systems and policy development in China. It provides a good contextual background on the development of the LTC system in China as well as the needs and preferences of LTC from family and older adults' perspectives. In addition, this issue covers the topic of evaluation of a recently developed long-term care nursing insurance and provides an example of family caregiving for persons with dementia within the Chinese context. The authors in this special issue also provided insights into the impact of the COVID-19 pandemic on older adults' life and LTC quality, and explored potential strategies to handle the challenges during and post-pandemic.


Asunto(s)
COVID-19 , Política de Salud , Servicios de Salud para Ancianos/organización & administración , Servicios de Salud para Ancianos/normas , Cuidados a Largo Plazo/organización & administración , Cuidados a Largo Plazo/normas , Mejoramiento de la Calidad , China , Humanos
11.
Journal of Clinical Medicine ; 9(12):4129, 2020.
Artículo en Inglés | ScienceDirect | ID: covidwho-984453

RESUMEN

Patients receiving mechanical ventilation for coronavirus disease 2019 (COVID-19) related, moderate-to-severe acute respiratory distress syndrome (CARDS) have mortality rates between 76–98%. The objective of this retrospective cohort study was to identify differences in prone ventilation effects on oxygenation, pulmonary infiltrates (as observed on chest X-ray (CXR)), and systemic inflammation in CARDS patients by survivorship and to identify baseline characteristics associated with survival after prone ventilation. The study cohort included 23 patients with moderate-to-severe CARDS who received prone ventilation for ≥16 h/day and was segmented by living status: living (n = 6) and deceased (n = 17). Immediately after prone ventilation, PaO2/FiO2 improved by 108% (p <0.03) for the living and 150% (p <3 ×10−4) for the deceased. However, the 48 h change in lung infiltrate severity in gravity-dependent lung zones was significantly better for the living than for the deceased (p <0.02). In CXRs of the lower lungs before prone ventilation, we observed 5 patients with confluent infiltrates bilaterally, 12 patients with ground-glass opacities (GGOs) bilaterally, and 6 patients with mixed infiltrate patterns;80% of patients with confluent infiltrates were alive vs. 8% of patients with GGOs. In conclusion, our small study indicates that CXRs may offer clinical utility in selecting patients with moderate-to-severe CARDS who will benefit from prone ventilation. Additionally, our study suggests that lung infiltrate severity may be a better indicator of patient disposition after prone ventilation than PaO2/FiO2.

12.
J Pediatr ; 226: 281-284.e1, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: covidwho-737186

RESUMEN

A 12-year-old girl with severe acute respiratory syndrome coronavirus 2 infection presented as phlegmasia cerulea dolens with venous gangrene. Emergent mechanical thrombectomy was complicated by a massive pulmonary embolism and cardiac arrest, for which extracorporeal cardiopulmonary resuscitation and therapeutic hypothermia were used. Staged ultrasound-assisted catheter-directed thrombolysis was used for treatment of bilateral pulmonary emboli and the extensive lower extremity deep vein thrombosis while the patient received extracorporeal membrane oxygenation support. We highlight the need for heightened suspicion for occult severe acute respiratory syndrome coronavirus 2 infection among children presenting with unusual thrombotic complications.


Asunto(s)
COVID-19/diagnóstico , Embolia Pulmonar/virología , Tromboflebitis/virología , Venas/patología , Trombosis de la Vena/virología , COVID-19/complicaciones , COVID-19/patología , COVID-19/terapia , Niño , Femenino , Gangrena/diagnóstico , Gangrena/virología , Humanos , Embolia Pulmonar/diagnóstico , Embolia Pulmonar/patología , Embolia Pulmonar/terapia , Tromboflebitis/diagnóstico , Tromboflebitis/patología , Tromboflebitis/terapia , Trombosis de la Vena/diagnóstico , Trombosis de la Vena/patología , Trombosis de la Vena/terapia
13.
Cancer ; 126(22): 4895-4904, 2020 11 15.
Artículo en Inglés | MEDLINE | ID: covidwho-704955

RESUMEN

BACKGROUND: In the wake of the coronavirus disease 2019 (COVID-19) pandemic, access to surgical care for patients with head and neck cancer (HNC) is limited and unpredictable. Determining which patients should be prioritized is inherently subjective and difficult to assess. The authors have proposed an algorithm to fairly and consistently triage patients and mitigate the risk of adverse outcomes. METHODS: Two separate expert panels, a consensus panel (11 participants) and a validation panel (15 participants), were constructed among international HNC surgeons. Using a modified Delphi process and RAND Corporation/University of California at Los Angeles methodology with 4 consensus rounds and 2 meetings, groupings of high-priority, intermediate-priority, and low-priority indications for surgery were established and subdivided. A point-based scoring algorithm was developed, the Surgical Prioritization and Ranking Tool and Navigation Aid for Head and Neck Cancer (SPARTAN-HN). Agreement was measured during consensus and for algorithm scoring using the Krippendorff alpha. Rankings from the algorithm were compared with expert rankings of 12 case vignettes using the Spearman rank correlation coefficient. RESULTS: A total of 62 indications for surgical priority were rated. Weights for each indication ranged from -4 to +4 (scale range; -17 to 20). The response rate for the validation exercise was 100%. The SPARTAN-HN demonstrated excellent agreement and correlation with expert rankings (Krippendorff alpha, .91 [95% CI, 0.88-0.93]; and rho, 0.81 [95% CI, 0.45-0.95]). CONCLUSIONS: The SPARTAN-HN surgical prioritization algorithm consistently stratifies patients requiring HNC surgical care in the COVID-19 era. Formal evaluation and implementation are required. LAY SUMMARY: Many countries have enacted strict rules regarding the use of hospital resources during the coronavirus disease 2019 (COVID-19) pandemic. Facing delays in surgery, patients may experience worse functional outcomes, stage migration, and eventual inoperability. Treatment prioritization tools have shown benefit in helping to triage patients equitably with minimal provider cognitive burden. The current study sought to develop what to the authors' knowledge is the first cancer-specific surgical prioritization tool for use in the COVID-19 era, the Surgical Prioritization and Ranking Tool and Navigation Aid for Head and Neck Cancer (SPARTAN-HN). This algorithm consistently stratifies patients requiring head and neck cancer surgery in the COVID-19 era and provides evidence for the initial uptake of the SPARTAN-HN.


Asunto(s)
Betacoronavirus , Infecciones por Coronavirus/epidemiología , Neoplasias de Cabeza y Cuello/cirugía , Recursos en Salud , Neumonía Viral/epidemiología , Triaje/métodos , Algoritmos , COVID-19 , Toma de Decisiones Clínicas , Consenso , Infecciones por Coronavirus/virología , Humanos , Cooperación Internacional , Pandemias , Neumonía Viral/virología , Reproducibilidad de los Resultados , Proyectos de Investigación , SARS-CoV-2 , Cirujanos
14.
F1000Res ; 9: 292, 2020.
Artículo en Inglés | MEDLINE | ID: covidwho-685664

RESUMEN

Enveloped viruses such as SAR-CoV-2 are sensitive to heat and are destroyed by temperatures tolerable to humans. All mammals use fever to deal with infections and heat has been used throughout human history in the form of hot springs, saunas, hammams, steam-rooms, sweat-lodges, steam inhalations, hot mud and poultices to prevent and treat respiratory infections and enhance health and wellbeing. This paper reviews the evidence for using heat to treat and prevent viral infections and discusses potential cellular, physiological and psychological mechanisms of action. In the initial phase of infection, heat applied to the upper airways can support the immune system's first line of defence by supporting muco-ciliary clearance and inhibiting or deactivating virions where they first lodge. This may be further enhanced by the inhalation of steam containing essential oils with anti-viral, mucolytic and anxiolytic properties. Heat applied to the whole body can further support the immune system's second line of defence by mimicking fever and activating innate and acquired immune defences and building physiological resilience. Heat-based treatments also offer psychological benefits and enhanced mental wellness by focusing attention on positive action, enhancing relaxation and sleep, inducing 'forced-mindfulness', and invoking the power of positive thinking and 'remembered wellness'. Heat is a cheap, convenient and widely accessible therapeutic modality and while no clinical protocols exist for using heat to treat COVID-19, protocols that draw from traditional practices and consider contraindications, adverse effects and infection control measures could be developed and implemented rapidly and inexpensively on a wide scale. While there are significant challenges in implementing heat-based therapies during the current pandemic, these therapies present an opportunity to integrate natural medicine, conventional medicine and traditional wellness practices, and support the wellbeing of both patients and medical staff, while building community resilience and reducing the likelihood and impact of future pandemics.


Asunto(s)
Infecciones por Coronavirus/terapia , Hipertermia Inducida , Neumonía Viral/terapia , Betacoronavirus , COVID-19 , Calor , Humanos , Aceites Volátiles , Pandemias , SARS-CoV-2 , Vapor
15.
Food Secur ; 12(4): 899-902, 2020.
Artículo en Inglés | MEDLINE | ID: covidwho-638312

RESUMEN

In addressing COVID-19, African governments should not forget the livelihoods as well as the food and nutrition security of their citizens. With over 70% of the workforce in the informal sector without any social protection and health insurance, the pandemic could have a devastating impact on income and livelihoods as well as food and nutrition security for workers up and down the food chain. There are ten steps African governments can take to ensure that their response to the disease takes food and nutrition security into account: 1. Protect food supply chains and consider them essential services; 2. Consider fiscal and monetary incentives; 3. Prioritize healthy diets; 4. Use food reserves wisely; 5. Keep food markets open while ensuring safety; 6. Use mobile cash transfers for social protection; 7. Protect farmers and food workers; 8. Prioritize gender equality; 9. Instill a sense of solidarity; and 10. Avoid export bans.

16.
Cancer ; 126(18): 4092-4104, 2020 09 15.
Artículo en Inglés | MEDLINE | ID: covidwho-635010

RESUMEN

Because of the national emergency triggered by the coronavirus disease 2019 (COVID-19) pandemic, government-mandated public health directives have drastically changed not only social norms but also the practice of oncologic medicine. Timely head and neck cancer (HNC) treatment must be prioritized, even during emergencies. Because severe acute respiratory syndrome coronavirus 2 predominantly resides in the sinonasal/oral/oropharyngeal tracts, nonessential mucosal procedures are restricted, and HNCs are being triaged toward nonsurgical treatments when cures are comparable. Consequently, radiation utilization will likely increase during this pandemic. Even in radiation oncology, standard in-person and endoscopic evaluations are being restrained to limit exposure risks and preserve personal protective equipment for other frontline workers. The authors have implemented telemedicine and multidisciplinary conferences to continue to offer standard-of-care HNC treatments during this uniquely challenging time. Because of the lack of feasibility data on telemedicine for HNC, they report their early experience at a high-volume cancer center at the domestic epicenter of the COVID-19 crisis.


Asunto(s)
COVID-19 , Neoplasias de Cabeza y Cuello/radioterapia , Telemedicina/métodos , COVID-19/transmisión , Procedimientos Quirúrgicos Electivos , Neoplasias de Cabeza y Cuello/diagnóstico por imagen , Neoplasias de Cabeza y Cuello/terapia , Humanos , Equipo de Protección Personal , Guías de Práctica Clínica como Asunto , Oncología por Radiación/organización & administración , Telemedicina/organización & administración
18.
Catheter Cardiovasc Interv ; 96(6): E602-E607, 2020 11.
Artículo en Inglés | MEDLINE | ID: covidwho-614999

RESUMEN

BACKGROUND: Following the surge of the coronavirus disease 2019 (COVID-19) pandemic, government regulations, and recommendations from professional societies have conditioned the resumption of elective surgical and cardiovascular (CV) procedures on having strategies to prioritize cases because of concerns regarding the availability of sufficient resources and the risk of COVID-19 transmission. OBJECTIVES: We evaluated the use of a scoring system for standardized triage of elective CV procedures. METHODS: We retrospectively reviewed records of patients scheduled for elective CV procedures that were prioritized ad hoc to be either performed or deferred when New Jersey state orders limited the performance of elective procedures due to the COVID-19 pandemic. Patients in both groups were scored using our proposed CV medically necessary, time-sensitive (MeNTS) procedure scorecard, designed to stratify procedures based on a composite measure of hospital resource utilization, risk of COVID-19 exposure, and time sensitivity. RESULTS: A total of 109 scheduled elective procedures were either deferred (n = 58) or performed (n = 51). The median and mean cumulative CV MeNTS scores for the group of performed cases were significantly lower than for the deferred group (26 (interquartile range (IQR) 22-31) vs. 33 (IQR 28-39), p < .001, and 26.4 (SE 0.34) vs. 32.9 (SE 0.35), p < .001, respectively). CONCLUSIONS: The CV MeNTS procedure score was able to stratify elective cases that were either performed or deferred using an ad hoc strategy. Our findings suggest that the CV MeNTS procedure scorecard may be useful for the fair triage of elective CV cases during the time when available capacity may be limited due to the COVID-19 pandemic.


Asunto(s)
COVID-19 , Cateterismo Cardíaco/tendencias , Enfermedades Cardiovasculares/terapia , Toma de Decisiones Clínicas , Técnicas de Apoyo para la Decisión , Necesidades y Demandas de Servicios de Salud/tendencias , Pandemias , Triaje/tendencias , Cateterismo Cardíaco/efectos adversos , Enfermedades Cardiovasculares/diagnóstico por imagen , Humanos , New Jersey , Estudios Retrospectivos , Medición de Riesgo , Factores de Riesgo , Tiempo de Tratamiento/tendencias
19.
Int J Equity Health ; 19(1): 93, 2020 06 10.
Artículo en Inglés | MEDLINE | ID: covidwho-592367

RESUMEN

BACKGROUND: The purpose of this study is to report the clinical features and outcomes of Black/African American (AA) and Latino Hispanic patients with Coronavirus disease 2019 (COVID-19) hospitalized in an inter-city hospital in the state of New Jersey. METHODS: This is a retrospective cohort study of AA and Latino Hispanic patients with COVID-19 admitted to a 665-bed quaternary care, teaching hospital located in Newark, New Jersey. The study included patients who had completed hospitalization between March 10, 2020, and April 10, 2020. We reviewed demographics, socioeconomic variables and incidence of in-hospital mortality and morbidity. Logistic regression was used to identify predictor of in-hospital death. RESULTS: Out of 416 patients, 251 (60%) had completed hospitalization as of April 10, 2020. The incidence of In-hospital mortality was 38.6% (n = 97). Most common symptoms at initial presentation were dyspnea 39% (n = 162) followed by cough 38%(n = 156) and fever 34% (n = 143). Patients were in the highest quartile for population's density, number of housing units and disproportionately fell into the lowest median income quartile for the state of New Jersey. The incidence of septic shock, acute kidney injury (AKI) requiring hemodialysis and admission to an intensive care unit (ICU) was 24% (n = 59), 21% (n = 52), 33% (n = 82) respectively. Independent predictors of in-hospital mortality were older age, lower serum Hemoglobin < 10 mg/dl, elevated serum Ferritin and Creatinine phosphokinase levels > 1200 U/L and > 1000 U/L. CONCLUSIONS: Findings from an inter-city hospital's experience with COVID-19 among underserved minority populations showed that, more than one of every three patients were at risk for in-hospital death or morbidity. Older age and elevated inflammatory markers at presentation were associated with in-hospital death.


Asunto(s)
Negro o Afroamericano/estadística & datos numéricos , Infecciones por Coronavirus/etnología , Infecciones por Coronavirus/terapia , Hispánicos o Latinos/estadística & datos numéricos , Grupos Minoritarios/estadística & datos numéricos , Neumonía Viral/etnología , Neumonía Viral/terapia , Anciano , COVID-19 , Femenino , Mortalidad Hospitalaria/etnología , Hospitalización/estadística & datos numéricos , Hospitales Urbanos , Humanos , Incidencia , Unidades de Cuidados Intensivos , Masculino , Persona de Mediana Edad , New Jersey/epidemiología , Pandemias , Estudios Retrospectivos , Medición de Riesgo , Resultado del Tratamiento
20.
J Aging Soc Policy ; 32(4-5): 403-409, 2020.
Artículo en Inglés | MEDLINE | ID: covidwho-574940

RESUMEN

An estimated 3.5 million direct care staff working in facilities and people's homes play a critical role during the COVID-19 pandemic. They allow vulnerable care recipients to stay at home and they provide necessary help in facilities. Direct care staff, on average, have decades of experience, often have certifications and licenses, and many have at least some college education to help them perform the myriad of responsibilities to properly care for care recipients. Yet, they are at heightened health and financial risks. They often receive low wages, limited benefits, and have few financial resources to fall back on when they get sick themselves and can no longer work. Furthermore, most direct care staff are parents with children in the house and almost one-fourth are single parents. If they fall ill, both they and their families are put into physical and financial risk.


Asunto(s)
Infecciones por Coronavirus/epidemiología , Personal de Salud/estadística & datos numéricos , Neumonía Viral/epidemiología , Betacoronavirus , COVID-19 , Personal de Salud/economía , Servicios de Atención de Salud a Domicilio/organización & administración , Humanos , Pandemias , Admisión y Programación de Personal/organización & administración , Instituciones Residenciales/organización & administración , SARS-CoV-2 , Factores Socioeconómicos
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